Service Offering

Service Offering

 

Access to imaging technologies and expertise in the National Microscopy Infrastructure is provided by four NMI Nodes. The Nodes offer a powerful portfolio of different state-of-the-art technologies in the fields of biological imaging. Each Node brings in a different combination of technologies as well as their expertise with distinct applications and methods.

Multimodal microscopy

 

Multimodal assimilation of technologies provides complementary and often unique information, spatial, structural, biochemical and biophysical details from the same target sample.

 

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Super-resolution Structured illumination microscopy (SIM)

 

SIM microscopy system can produce twice the resolution of conventional optical microscopes

 

 

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Singel molecule localization microsopy

 

Within the NMI infrastructure we have the equipment and experience to performe single molecule localization microscopy with both PALM and STORM.

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STED - Stimulated emission depletion microscopy

 

At the NMI infrastructure we have the equipment and experience to perform STED in a diversity of sample preparations.

 

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CLEM - Correlative light electron microscopy

 

Within NMI we have the equipment and experience to performe CLEM using transmission electron microscopy (TEM) and scanning electon microscopy (SEM)

 

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CLM-AFM - Correlative Light and Atomic Force Microscopy

 

Within the NMI infrastructure we have the equipment and experience to performe CLM-AFM

 

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High throughput confocal microscopy

 

The NMI infrastructure enables large number of fixed samples to be imaged in 96 or 384 plate format using laser scanning confocal microscopy.

 

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IVM - Intravital microscopy

 

More information to come.

 

 

 

FCS/FCCS - Fluorescence correlation spectroscopy

 

Measures diffusion coefficients and concentrations of fluorescent molecules in solution and in living cells by monitoring fluorescence intensity fluctuations in a single spot.

 

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RESOLFT - Reversible Saturable Optical Fluorescence Transitionsmicroscopy

 

More information to come.

 

 

 

Light sheet microscopy

 

Light Sheet Fluorescence Microscopy permits optical sectioning of large samples, with little to no phototoxicity or photobleaching and high temporal resolution.

 

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Cryo electron microscopy

 

Within the NMI infrastructure we have the equipment and experience to performe Cryo EM

 

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